Applicable protein formats
Supports IgG, VHH, and scFv with a hydrophobic core and aromatic amino acids; specific molecular formats and sample requirements are confirmed at project kickoff.
Thermostability(includes expression)
Price
from ¥660 / protein
Delivery
12–14 days
Delivered data
- Melting curves
- Tm values
This service includes antibody expression, purification, and thermostability testing, allowing thermostability to be compared across antibody sequences.
High-sensitivity assay
Use nanoDSF across a wide temperature range to monitor protein unfolding.
Thermostability comparison
Compare thermostability differences across antibody sequences.
Expression included
Complete expression, purification, and QC before thermostability assays.
Experiment workflow
- 1
Day 0
Submit designs
Submit candidate antibody sequences.
- 2
Day 1–6
Experiment preparation
Design and order DNA constructs for the corresponding variants.
- 3
Day 7–9
Protein expression
Complete protein expression, purification, and QC.
- 4
Day 10–12
Stability assay
Run the nanoDSF assay and collect the data.
- 5
Day 13–14
Review and deliver
Review results and deliver a structured data package.
Delivered data
Melting curves
Thermal unfolding curves as temperature increases.
Tm values
Melting temperatures calculated from unfolding curves.
Thermostability comparison
Clearly compare thermostability differences across antibody sequences.
Expression results
Expression and purification results.
Thermostability quote
Configure project parameters and view a reference quote instantly.
Service selection
Thermostability analysisExpression and purification + concentration/purity + a thermostability testing package. Assess candidate sequence thermostability early.
Sequence count
Choose how many sequences to assay. The unit price follows the volume band.
4896192384768
T1¥1,150 / protein
Replicates
Select replicate wells for the same antibody sequence. 1 means a single well with no replicate.
Delivery
Standard delivery12–14 days
Experiment layout
48 sequences (1x)
Target 1
Theoretical minimum 1 × 96-well plates / target